NanoFUSE Biologics is the first and only FDA-Approved combination of synthetic bioactive ceramic 45S5 bioglass osteobiologics plus demineralized bone matrix (DBM) used for regenerative bone formation, promoting fusion and bone healing. NanoFUSE, when combined with an aqueous body fluid, forms a 3D ultra porous calcium hydroxyapatite layer for bone formation in as early as 24 hours.