Engineered to Activate Bone.
Advancing Synthetic Bioactive Glass Osteobiologics Applications
The first and only FDA-cleared synthetic 45S5 bioactive glass osteobiologic uniquely formulated to combine with DBM to amplify regenerative bone formation.
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NanoFUSE forms a 3D ultra-porous calcium hydroxyapatite layer in as early as 24 hours — initiating a biologically active surface designed for bone integration.
A New Standard In Synthetic Osteobiologics
NanoFUSE Biologics activates DBM biology for a robust effectiveness.
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By combining nanostructured bioactive glass with DBM compatibility, NanoFUSE represents a shift toward intelligent regenerative materials engineered for early surface activation and predictable performance.
Why NanoFuse Biologics
[1] Bioactive by Design
Upon contact with aqueous body fluids, NanoFUSE begins ionic exchange that leads to rapid formation of a calcium hydroxyapatite (CHA) layer — the same mineral phase found in native bone.
[2] Synthetic Precision
Manufactured 45S5 bioactive glass ensures consistency, reliability, and no donor site morbidity or disease transmission risk.
[3] Amplifies DBM Performance
NanoFUSE is uniquely formulated to combine with demineralized bone matrix (DBM), enhancing scaffold architecture and supporting regenerative signaling.
The Science
Snapshot
FROM IMPLANTATION TO INTEGRATION
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Surface activation upon fluid exposure
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Formation of ultra-porous CHA layer (as early as 24 hours)
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Osteoblast attachment and proliferation
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Progressive remodeling into native bone
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NanoFUSE transforms from a synthetic ceramic into a biologically active regenerative interface
Clinical Application
FILLS BONE VOIDS & DESIGN FOR USE IN
Spine
Orthopedics
Foot & ankle
​Built for surgeons seeking scientifically proven synthetic bioactive regeneration.
